Some people are able to tuck into chocolate every day and not
gain weight, while others struggle to keep their weight down regardless
of what they eat. Exactly why this is has been unclear, but now
researchers point to a genetic mutation as the cause.
Researchers from the University of Cambridge in the UK say that mutation
of a gene called KSR2 may cause continued hunger pangs in patients who
are obese, as well as slow their metabolism - the rate at which the body
burns calories.
These findings could provide some explanation for the increase in childhood obesity. According to the Centers for Disease Control and Prevention
(CDC), the rate of childhood obesity has more than doubled in the US in
the past 30 years. The increase has prompted researchers to identify
possible obesity causes and interventions.
Previous studies have demonstrated that deleting the KSR2 gene in mice
caused them to develop obesity. This highlighted KSR2 as an important
factor in regulating energy balance and metabolism.
But until now, it has been unclear as to whether this gene has the same effect in human subjects.










































